Exocrine pancreatic function as determined in a same-day test with use of bentiromide and p-aminosalicylic acid.
نویسندگان
چکیده
We describe a new approach to the bentiromide test of exocrine pancreatic function, p-Aminosalicylic acid (PAS), a compound closely related to the bentiromide fragment p-aminobenzoic acid (PABA), is used as a marker of the pharmacokinetic behavior of PABA to derive a PABA excretion index. This index is identical to that derived with [14C]-PABA. Concentrations of both PABA and PAS are measured in urine by "high-performance" liquid chromatography, which avoids the drug interferences encountered with established assays of PABA. We discuss the practical and diagnostic advantages of this new approach to the bentiromide test.
منابع مشابه
Simplified oral pancreatic function test.
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 32 6 شماره
صفحات -
تاریخ انتشار 1986